QuestionSynthesis / Friedel–Crafts with blocking group
The correct sequence of reactions to accomplish the multi-step synthesis of 1-isobutyl-2-methylbenzene from benzene is
Benzene ⟶⟶ 1-Isobutyl-2-methylbenzene
- (a) [1] (CH₃)₂CHCOCl / AlCl₃; [2] HCl, Zn(Hg)/heat; [3] dilute H₂SO₄; [4] CH₃Cl, AlCl₃; [5] fuming H₂SO₄
- (b) [1] CH₃Cl, AlCl₃; [2] dilute H₂SO₄; [3] (CH₃)₂CHCOCl / AlCl₃; [4] HCl, Zn(Hg)/heat; [5] fuming H₂SO₄
- (c) [1] (CH₃)₂CHCl / AlCl₃; [2] fuming H₂SO₄; [3] CH₃Cl, AlCl₃; [4] dilute H₂SO₄
- (d) [1] (CH₃)₂CHCOCl / AlCl₃; [2] HCl, Zn(Hg)/heat; [3] fuming H₂SO₄; [4] CH₃Cl, AlCl₃; [5] dilute H₂SO₄
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