QuestionOrganic / SN2 stereochemistry (Hughes experiment)
In an experiment, the rate of racemization of 2-iodooctane by sodium iodide (Na¹³¹I) in acetone was compared with the rate of incorporation of radioactive iodine into 2-iodooctane
If we assume that each incorporation proceeds stereospecifically with inversion of configuration then we can conclude that
- (a) There will not be any observable racemization
- (b) The rate of racemization will be equal to the rate of incorporation of radioactive iodine
- (c) The rate of racemization will be twice the rate of incorporation of radioactive iodine
- (d) The rate of incorporation of radioactive iodine will be twice the rate of racemization
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